And now, transcriptomics
by
Garlow SJ.
Department of Psychiatry and Behavioral Science,
Emory University School of Medicine,
1639 Pierce Drive, Suite 4000,
Atlanta, GA 30322, USA.
Neuron 2002 Apr 25;34(3):327-8


ABSTRACT

In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims. The authors speculate on a possible serotonergic mechanism controlling 5-HT2C pre-mRNA editing.
5-HT2c
Agomelatine
21st century
RNA silencing
Nutrigenomics
Transcriptomics
Antidepressants
Pharmacogenetics
Pharmacogenomics
Suicide, serotonin and SSRIs
How heritable is depression?
Genomics and mood disorders
Alcohol, suicide and serotonin
Serotonergic genes and suicide
The serotonin 5-HT2C receptors
Antidepressants and the suicide rate


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