Tranylcypromine addiction:
a case report and review

by
Briggs NC, Jefferson JW, Koenecke FH
Department of Psychiatry,
University of Wisconsin Medical School,
Madison 53792.
J Clin Psychiatry 1990 Oct; 51(10):426-9


ABSTRACT

The authors report a case of tranylcypromine addiction and review the literature on the subject. Since the drug was first marketed in 1960, a total of 18 cases have been described. Predisposing risk factors and potential mechanisms for addiction are discussed. Given the current trend toward using tranylcypromine more frequently and in higher therapeutic doses for refractory depression, a greater index of suspicion for self-medication with this drug is warranted.
MAOIs
Dopamine
Bupropion
Anhedonia
Amineptine
Nomifensine
Noradrenaline
MAOI interactions
Retarded depression
Tranylcypromine: structure
Tranylcypromine dependence
Tranylcypromine v moclobemide
Tranylcypromine and anergic depression
Tranylcypromine (Parnate): mechanisms
Tranylcypromine, moclobemide and dopamine
Tranylcypromine, sleep and anergic bipolar depression
High-dose tranylcypromine (Parnate) for refractory depression


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