The use of tiagabine in affective disorders
Carta MG, Hardoy MC, Grunze H, Carpiniello B.
Psychiatric Unit, Department of Public Health,
University of Cagliari, Via Liguria 13, 09127 Cagliari, Italy.
Pharmacopsychiatry 2002 Jan;35(1):33-4
ABSTRACTWe reviewed the available literature on the efficacy of a novel anticonvulsant, Tiagabine (TGB), in the treatment of bipolar disorder. Study results indicate that TGB does not represent a valid option in acute mania due its required slow, progressive titration. More rapid titration schemes may lead to severe complications. TGB may be an option as an adjunct long-term treatment approach in refractory patients, but further studies are clearly needed to support this.Options
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