Self-medication with gamma-hydroxybutyrate
to reduce alcohol intake

by
Glisson JK, Norton J.
Department of Neurology and Psychiatry,
University of Mississippi Medical Center, Jackson, USA.
South Med J 2002 Aug;95(8):926-8


ABSTRACT

We describe a 52-year-old man who self-medicated with gamma-hydroxybutyrate (GHB), a widely available illicit substance, to obtain a decrease in ethanol consumption. He successfully reduced his ethanol intake over a 3-month period, but he was unable to sustain abstinence. Although case reports on the use of GHB to induce euphoria have been published, this is the first report of GHB self-medication to facilitate ethanol abstinence. This report highlights the importance of considering GHB self-medication not only for euphoric and mood altering effects, but also as a potential treatment for ethanol intake reduction.
GHB
GABA
Opioids
Reward
Alcohol
Dopamine
21st century
GHB and GABA
GHB withdrawal
GHB and cocaine
Drugs and reward
GHB and alcoholism
GHB and narcolepsy
Rodent polydrug abusers
GHB and growth hormone
Nicotine-ethanol interaction
Drink, drugs and sex in antiquity
GHB: use, abuse and withdrawal
GHB as a signalling molecule in brain


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