Basic psychopharmacology of antidepressants, part 2: Estrogen as an adjunct to antidepressant treatment
by
Stahl SM
Clinical Neuroscience Research Center
and the Department of Psychiatry,
University of California,
San Diego 92122, USA.
J Clin Psychiatry 1998; 59 Suppl 4:15-24


ABSTRACT

Estrogen exerts profound effects upon behavior by interacting with neuronal estrogen receptors. Changes in estrogen levels over a woman's life cycle are linked not only to behavioral fluctuations, but potentially to the onset or recurrence of mood disorders. The modern psychiatric evaluation of women requires obtaining a complete reproductive history, including details of hormone treatments, while identifying reproductive events as triggers of affective disorder episodes. While guidelines for the use of reproductive hormones in psychiatry are just evolving, administration of estrogen as an adjunct to antidepressants is an exciting possibility for expanding the frontiers of psychiatry into the field of women's health.
SERMs
Options
21st Century
SSRIs and PMT
Sertraline and PMT
Fluoxetine and PMT
Tryptophan and PMT
Oestrogen: structure
Oestrogens and the menopause
Estrogenic compounds as antidepressants


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