Adjunctive bright light in non-seasonal major depression:
results from clinician-rated depression scales

by
Martiny K, Lunde M, Unden M, Dam H, Bech P.
Psychiatric Research Unit,
Frederiksborg General Hospital,
Hilleroed, Denmark.
kmar@fa.dk
Acta Psychiatr Scand. 2005 Aug;112(2):117-25.


ABSTRACT

OBJECTIVE: To investigate the use of bright light therapy as an adjunct treatment to sertraline in non-seasonal major depression. METHOD: In a randomised double-blind trial, 102 patients were treated for 5 weeks with either white bright light (10 000 lux, 1 h daily) or red dim light (50 lux, 30 min daily). All patients were treated with sertraline in a fixed dose of 50 mg daily. The clinician-rated depression scales used were the Hamilton Depression Rating Scale (HAM-D17), Hamilton six-item subscale (HAM-D6), Melancholia Scale (MES) and the seven 'atypical' items from the SIGH-SAD. RESULTS: One-hundred and two patients were included in the study. Analyses showed that the reduction in depression scores in the bright light group was statistically significantly larger than in the dim light group on all scales. The scale most sensitive at endpoint was the HAM-D(6), which includes the core symptoms of depression. CONCLUSION: The study results support the use of bright light as an adjunct treatment to antidepressants in non-seasonal depression.


Kava
SAMe
Folate
Ginkgo
Reward
Valerian
Exercise
Cannabis
Herbalife
Moodfoods
Hypericum
Herbal highs
St John's wort
Panax ginseng
Passion flower
Slimming drugs
Herbal medicines
Natural supplements
Psychoactive aspirin?
Bright light vs fluoxetine (Prozac)
The circadian basis of winter depression
Light therapy with blue wavelength LEDs
How light deprivation causes depression
Seasonal affective disorder (SAD): a clinical update



Refs
and further reading

HOME
HedWeb
Nootropics
erythroxylum-coca.com
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhapiness?
Utopian Surgery?
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World

The Good Drug Guide
The Good Drug Guide

The Responsible Parent's Guide
To Healthy Mood Boosters For All The Family