Reversible pathologic jealousy (Othello syndrome)
associated with amantadine

by
McNamara P, Durso R.
Department of Neurology,
Boston University School of Medicine, MA
J Geriatr Psychiatry Neurol 1991 Jul-Sep;4(3):157-9


ABSTRACT

We describe a case of pathologic jealousy (Othello syndrome) in a patient with Parkinson disease, which abated after discontinuing amantadine. We indicate that early recognition and treatment of the syndrome in this disease may avert physical violence. We also believe that our report further suggests a link between this specific behavioral disorder and dopaminergic activity.
Jealousy
Serotonin
Dopamine
Memantine
Amantadine
Antidepressants
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