Aggressive pharmacologic treatment of pain
by
Pappagallo M
Department of Neurology,
Johns Hopkins University School
of Medicine,
Baltimore, Maryland, USA.
Rheum Dis Clin North Am 1998 Feb; 25(1):193-213, vii
ABSTRACT
In this article, the author outlines the pharmacology of nociception and discusses the two major classes of drugs used for pain control: opioids and
nonopioid analgesics. In order to provide satisfactory pain relief and prevent
the possible sequelae of untreated pain, physicians must possess both knowledge
and expertise in the use of opioid and nonopioid analgesics. Opioid analgesics
have been underused in the management of pain. Opioids have a higher analgesic
potency and wider range of indications than any of the other currently available
medications for pain control. The second class of drugs, the nonopioid
analgesics and adjuvants, has recently expanded to include new and potentially
beneficial medications. This article furthers the understanding on how to use
analgesics for a prompt, safe, and effective pharmacologic treatment of acute
and chronic pain.
Opioids
Morphine
Cannabis
Gabapentin
Venlafaxine
Fibromyalgia
Buprenorphine
Amphibian pain
OTC analgesics
Antidepressants
Pain measurement
The pain of fibromyalgia
Enkephalinase inhibitors
Depression and chronic pain
Cannabinoids, opioids and pain
Antidepressants for pain-relief
The magic millimeter? Locating the hedonic hotspot
Venlafaxine (Effexor) analgesia and the opioid system
Tricyclic antidepressants as long-acting local anesthetics
Refs
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