Buspirone: future directions
by
Apter JT, Allen LA
Princeton Biomedical Research, PA, New Jersey, USA.
J Clin Psychopharmacol 1999 Feb; 19(1):86-93
ABSTRACT
The Food and Drug Administration approved the use of buspirone for
generalized anxiety disorder (GAD) in 1986. Since then, numerous studies have
examined the efficacy and safety of buspirone for patients with not only
generalized feelings of anxiety, but also panic disorder, major depressive
disorder, obsessive-compulsive disorder, body dysmorphic disorder, social
phobia, posttraumatic stress disorder, selective serotonin reuptake
inhibitor-induced adverse events, dementia, behavioral disturbances, attention
deficit-hyperactivity disorder, and tobacco dependency. Although relatively few
placebo-controlled trials have been conducted on patients with problems other
than GAD, an ever-growing body of research suggests future directions for the
use of buspirone. This article reviews the body of research relating to new uses
for buspirone.
OCD
PTSD
ADHD
SSRIs
5-HT1a
Anxiety
Gepirone
Serotonin
Ipsapirone
Eltoprazine
Aggression
Future anxiolytics
Buspirone plus pindolol
Buspirone: mechanisms
Buspirone v clorazepate
Buspirone plus venlafaxine
Buspirone: pharmocokinetics
Buspirone and 5-HT1a receptors
Buspirone (Buspar): prescribing information (PDF)
Buspirone (Buspar) extended- v immediate-release
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